Projects

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Thrusts

Project Specifics

Specification

  • Applying Hardware Description Languages to Genetic Circuit Design
    • Cello is a Clotho App for translating a Verilog description of a combinational logic circuit into physical genetic regulatory network.
  • Domain Specific Languages for Synthetic Biology
    • Eugene is a domain specific language for synthetic biological systems which uses rules to do design space exploration.
  • Formal Specification and Verification Framework for Synthetic Biology Design Automation

Design

  • Feature, Signal, and Part Matching
    • Matchmaker is a Clotho app for translating an abstract genetic regulatory network into a specific sequence of genetic parts.
  • Schematic-based Visual Design
    • Spectacles is a Clotho App which acts as a genetic regulatory network schematic design tool.
  • Design algorithms
    • Algorithm Manager is a Clotho App which houses a variety of design algorithms.
  • Invertase placement algorithms
    • Trumpet is a Clotho App for placing invertases to explore configurations of genetic circuits.
  • Design for X
    • DFX examines how genetic designs can be automatically analyzed to improve robustness, reliability, and testability.
  • Ontology/Family Classification of Synthetic Biological Designs

Assembly

  • Protocol Capture and Automation
    • Puppeteer is a language for specifying biological protocols and a software stack for executing them on a liquid handling robot.
    • Puppet Show is a Clotho App.
  • Assembly Methods
    • MoClo is an assembly method that allows the user to ligate up to six DNA Parts together in one reaction

Data Management

  • Characterization based workflow for the forward engineering of biological systems.

Design Drivers

Community

Sponsors


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